PhD Studentship in Biochemistry at Department of Microbial Physiology, University of Groningen
The University of Groningen as Partner of the Top-Institute Pharma (The Netherlands) offers a PhD position in the Department of Analytical Biochemistry to work on a project entitled:
Acute and chronic inflammatory responses induced by smoking in individuals being susceptible and non-susceptible for development of Chronic Obstructive Pulmonary Disease (COPD): from specific disease phenotyping towards novel tailor-made therapy
This PhD position is embedded within a larger collaborative project between academic institutes and the pharmaceutical industry within the framework of a nationally funded centre of excellence the Top Institute Pharma (www.tipharma.nl). The PhD project will focus on developing novel methodologies to study the proteome of human biological samples with relevance to COPD, such as induced sputum, epithelial cells obtained by bronchial brushing and tissue biopsies. Special attention will be paid to sample preparation and the high efficiency separation of proteins and peptides by nano-High-Performance Liquid Chromatography (HPLC) coupled to mass spectrometry using state-of-the-art equipment (e.g. chipLC-Q-TOF-MS, nanoLC-Orbitrap-MS). The project will be executed in close collaboration with the Groningen Research Institute of Asthma and COPD (Prof. Dr. Dirkje Postma; www.graduateschoolguide.nl/html/research/institutes/griac/home.htm).
